Scientific program

Wednesday, May 15, 2019

Hour

Event

15:00

Registration office opens

16:00-16:30

Opening Ceremony

16:30-17:30

Plenary Opening Lecture

Chair: Ana Gomis

Speaker: Thomas Voets

Laboratory of Ion Channel Research, KU Leuven

Title: TRP channels in acute and inflammatory pain

Symposium 1: Mechanotransduction and piezo channels 

Chair: Ana Gomis

17:30-18:00

Miguel A. Valverde (Universitat Pompeu Fabra)

Mechano/osmosensitive ion channels in cell migration and invasion

18:00-18:30

Jorge Fernández-Trillo (Inst. Neurociencias de Alicante)

Piezo2 mediates corneal noxious mechanosensation

18:30-19:00

Mark Hoon (National Institute of Dental and Craniofacial Research, Bethesda, MD, USA)

Molecular and functional characterization of Piezo2 splicing

19:00-19:15

Lucia Alonso-Carbajo (Lab Ion Channel Res., KU Leuven-VIB Center for Brain & Dis. Resea., Leuven, Belgium/IBGM-Universidad Valladolid/CSIC)

Activation of the cation channel TRPM3 in sensory nerves induces vasodilation of resistance arteries

19:15-19:30

Lola Rueda-Ruzafa (CINBIO-Universidad de Vigo)

Increasing temperature activates TREK potassium channels in nodose ganglion neurons

19:30-19:45

Maria Giustina Rotordam (Nanion Technologies GmbH, Munich, Germany)

A high-throughput patch clamp method to investigate Piezo1 channels from healthy and anaemic red blood cells

20:00-21:00

Welcome Reception

Thursday, May 16, 2019

Hour

Event

Symposium 2: Ion channels: from structure and function to drug discovery

Chair: Pilar de la Peña

9:00-9:30

Francisco Barros (Universidad de Oviedo)

The cardiac hERG K+ channel: a journey from cell biology to structure and function

9:30-10:00

Donato del Camino Fernández-Miranda (Rheostat, Cambridge, MA, USA)

Targeting TRP channels for drug development

10:00-10:15

Aravind Kshatri (Universidad de La Laguna)

Fragile X mental retardation protein differentially regulates the biophysical properties of BK channels

10:15-10:30

Pablo Doñate-Macián (Universitat Pompeu Fabra)

The TRPV4 channel links calcium influx to DDX3X activity and viral infectivity

10:30-10:45

Fabiana Scornik (Universitat de Girona)

Cardiac sodium current is severely impaired in induced pluripotent stem cell-derived cardiomyocytes from Brugada Syndrome patients

10:45-11:00

Jesusa Capera (Universitat de Barcelona)

Mitochondrial Kv1.3 channels in apoptosis

11:00-12:00

Coffee break and posters

Symposium 3: Calcium signaling and cell function

Chair: Tarik Smani

12:00-12:30

Angel Nadal (Universidad Miguel Hernández)

Bisphenol-A modulates ion channel expression and function via estrogen receptor β in mouse pancreatic beta cells

12:30-13:00

María Fernández Velasco (Hospital Universitario La Paz)

Immune system and Ca2+ signaling in cardiac cells: Role of NOD1

13:00-13:15

Carmen Delgado (Biomed Res. Inst. Alberto Sols (CSIC)

Beneficial effects of paricalcitol on cardiac dysfunction and deleterious remodeling after established heart failure

13:15-13:30

Marta Martín-Bórnez (Inst. de Biomedicina de Sevilla)

Essential role of Orai1 and Saraf in vascular remodeling

13:30-13:45

Carles Solsona (Universitat de Barcelona)

Calcium dependent Chloride Channels (CaCC) as a target of a bacterial toxin

13:45-14:00

Ricardo Gómez (Universidad de La Laguna)

NMDAR and BK channels form Ca2+ nanodomains in basal dendrites of barrel cortex layer 5 pyramidal neurons to control synaptic excitability and plasticity

14:00-15:30

Lunch break

Symposium 4: Store-operated channels

Chair: Carlos Villalobos

15:30-16:00

Juan A. Rosado (Universidad de Extremadura)

Role of TRPC6 in breast cancer cell Ca2+ homeostasis

16:00-16:30

Carlos Villalobos (IBGM-Universidad de Valladolid/CSIC)

Store-operated channels in pituitary physiology

16:30-16:45

Isaac Jardín (Universidad de Extremadura)

EFHB regulates store-operated calcium entry, migration and proliferation in breast cancer cells

16:45-17:00

Lucia G. Gutiérrez (IBGM-Universidad de Valladolid/CSIC)

Reversing Ca2+ channel remodeling in colon cancer cells by polyamine biosynthesis inhibition

17:00-17:15

Isabel Mayoral-González (Inst. Biomedicina de Sevilla)

Dysregulation of ion channels expression associated with the adverse cardiac remodeling due to heart revascularization

17:15-17:30

José J. López (Universidad de Extremadura)

A new role for adenylate cyclase 8 as modulator of store-operated calcium entry

17:30-18:30

Plenary Lecture

Chair: Juan A. Rosado

Speaker: Christoph Romanin

Johannes Kepler University Linz, Linz, Austria

Title: Regulation of STIM1 and Orai1 function

18:30-20:30

Visit to the Monumental city of Cáceres

21:00-23:00

CONGRESS DINNER

Friday, May 17, 2019

Hour

Event

Symposium 5: Cardiac ion channels are not alone

Chair: Eva Delpón

9:00-9:30

José Jalife (University of Michigan)

Dysfunction of the Cardiac Kir2.1-NaV1.5 channelosome trafficking underlies arrhythmia susceptibility in the Andersen-Tawil Syndrome

9:30-10:00

Eva Delpón/Ricardo Caballero (Univ. Complutense de Madrid)

The odds couple: Nav1.5 and Kir2.x channels

10:00-10:15

Sendoa Tajada (University of California School of Medicine, CA, USA)

BIN1 induces the formation of T-tubules, Cav1.2 channel clusters and adult-like Ca2+ release units in developing cardiomyocytes

10:15-10:30

Clara Serrano-Novillo (Universitat de Barcelona)

Endoplasmic reticulum-plasma membrane junctions hub the Iks complex

10:30-11:30

Coffee break and posters

Symposium 6: Drug discovery and ion channel pharmacology

Chair: Asia Fernández

11:30-12:00

Francisco Nieto López (Universidad de Granada)

Title: Voltage-gated sodium channels as pharmacological targets for neuropathic pain relief

12:00-12:30

Rosario Gonzalez Muñiz (Inst. de Química Médica, CSIC)

Title: β–Lactam TRPM8 antagonists prevent chemotherapy-induced cold allodynia

12:30-12:45

Mercè Izquierdo-Serra (Universitat Pompeu Fabra)

Low-throughput evaluation of novel Cav2.1-modulators to treat Hemiplegic Migraine

12:45-13:00

Diego A. Peraza (Instituto de Investigaciones Biomédicas Alberto Sols (IIBM), CSIC-UAM)

Identification of IQM-266, a novel DREAM ligand that modulates KV4 currents

13:00-14:00

Closing Lecture

Chair: Juan A. Rosado

Speaker: Annarosa Arcangeli

Università degli Studi di Firenze, Italia

Title: Ion channel conformations regulate intracellular signaling and cell fate in tumors

14:00-14:30

RECI Assembly 

14:30-15:30

Lunch and Farewell